Biofreeze is a cryogel which uses cold therapy to give fast, topical relief from pain associated with sports injuries, aching joints, arthritis, back and neck pain, and stiff and aching muscles. Biofreeze contains ILEX, which works by dramatically cooling the affected areas, achieving pain relief and reducing blood supply to the area and by reducing the ability of the nerve to conduct pain stimuli. The gel fully penetrates joints and muscles in three minutes and gives effective pain relief for hours without the need for pills.